Efficient parameterization of large-scale mechanistic models enables drug response prediction for cancer cell lines

نویسندگان

  • Fabian Fröhlich
  • Thomas Kessler
  • Daniel Weindl
  • Alexey Shadrin
  • Leonard Schmiester
  • Hendrik Hache
  • Artur Muradyan
  • Moritz Schütte
  • Ji-Hyun Lim
  • Matthias Heinig
  • Fabian J. Theis
  • Hans Lehrach
  • Christoph Wierling
  • Bodo Lange
  • Jan Hasenauer
چکیده

Institute of Computational Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany Chair of Mathematical Modeling of Biological Systems, Center for Mathematics, Technische Universität München, 85748 Garching, Germany Alacris Theranostics GmbH, 12489 Berlin, Germany Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany Dahlem Centre for Genome Research and Medical Systems Biology, 12489 Berlin, Germany NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, 0450 Oslo, Norway Division of Mental Health and Addiction, Oslo University Hospital, 0450 Oslo, Norway

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تاریخ انتشار 2017